Disease: Metastatic human epidermal growth factor 2 positive carcinoma of breast
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
MIR21 microRNA 21 0.363 0.846
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
FCGR3A P08637 Fc fragment of IgG receptor IIIa Cell adhesion 3.7E-06 0.432 0.962
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
DM1-AS DM1 locus antisense RNA 0.839 0.115
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962